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Evaluation of anti-inflammatory activity in Wistar rats using ethanolic extract of moringa leaves by Carrageenan induced inflammation

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  • Evaluation of anti-inflammatory activity in Wistar rats using ethanolic extract of moringa leaves by Carrageenan induced inflammation

P VIJAY KUMAR *, N SHEKAR, V PRANAY KUMAR, P RADHIKA, M ABHISHEK PATIL and Y GOPI KRISHNA

Department of Pharmacology, Malla Reddy Institute of Pharmaceutical Sciences, Maisammaguda, Dhulapally, Post via Kompally, secunderabad-500 100.

Research Article

International Journal of Science and Research Archive, 2025, 15(03), 1320-1329

Article DOI: 10.30574/ijsra.2025.15.3.1441

DOI url: https://doi.org/10.30574/ijsra.2025.15.3.1441

Received on 05 May 2025; revised on 14 June 2025; accepted on 16 June 2025

Around the world, inflammatory disorders are a leading source of morbidity and disability among workers. Standard steroidal and non-steroidal anti-inflammatory medication treatments for inflammation carry the same risk of harming different organ systems. It has been suggested that the herbal plant Moringa oleifera can effectively treat a variety of inflammatory diseases. However, there aren't enough scientific studies to support these assertions.
From the beginning of human civilization, medicinal plants have been used to treat a variety of illnesses. According to the World Health Organization, almost 80% of people in underdeveloped nations struggle to pay for synthetic medications and must rely on traditional medicines, mostly made from plants, to meet their basic medical needs. In numerous tropical and subtropical nations, Moringa oleifera LAM (Moringaceae) has been utilized as a traditional medicine. It is a very nutrient-dense vegetable that may be used to cure microbiological infections, poisonous bites, and rheumatism. Researchers looked into the Methanol extract of Moringa oleiferous (MEMO) anti-inflammatory properties. Using a plethysmometer, In order to investigate the anti-inflammatory properties of ethanolic extract of Moringa oleifera leaves (EEMO) in experimentally induced inflammation in albino rats, the current study was conducted. The results of the present study revealed that oral administration of EEMO exhibited anti-inflammatory effect in the models studied

Anti-inflammatory; Albino rats; Moringa oleifera; Inflammation; Paw oedema; Plethysmometer

https://journalijsra.com/sites/default/files/fulltext_pdf/IJSRA-2025-1441.pdf

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P VIJAY KUMAR, N SHEKAR, V PRANAY KUMAR, P RADHIKA, M ABHISHEK PATIL and Y GOPI KRISHNA. Evaluation of anti-inflammatory activity in Wistar rats using ethanolic extract of moringa leaves by Carrageenan induced inflammation. International Journal of Science and Research Archive, 2025, 15(03), 1320-1329. Article DOI: https://doi.org/10.30574/ijsra.2025.15.3.1441.

Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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